Ipamorelin
Selective ghrelin receptor (GHS-R1a) agonist studied for pulsatile growth hormone release.
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Description
Ipamorelin is a pentapeptide belonging to the growth hormone secretagogue class, acting as a selective agonist at the ghrelin receptor (GHS-R1a) on pituitary somatotrophs. Unlike earlier-generation GH secretagogues, research has characterized Ipamorelin as producing GH pulses with minimal concurrent elevation of cortisol, prolactin, or acetylcholine — an effect attributed to its high receptor selectivity. Preclinical studies have examined its GH-release profile relative to GHRP-2 and GHRP-6, reporting comparable GH secretion with a narrower off-target signaling footprint. Supplied for in-vitro laboratory research only — not for human or veterinary use.